![]() 1986 ).Īnaphylaxis beginning with abdominal pain, followed by pharyngeal pruritis and facial oedema with nasal congestion and finally generalised urticaria and impaired respiration (Kanny et al. 1979 ).ĭiffuse pruritus, urticaria, angioedema, nausea and vomiting, chest tighness and wheezing followed by vascolar collapse and loss of consiousness in one patient and diffuse pruritus, urticaria and facial angioedema in another (Halsey et al. Two major allergens with molecular weights of 6 and 50 kDa were purifi ed and identifi ed as albumin and vicilin, respectively.Tingling of lips, laryngeal oedema, generalised angioedema, generalised urticaria, bronchospasm, abdominal pain (Noyes et al. Most patients (70%) were monosensitized to this nut. In this article, 80% of allergic reactions to pine nut in the ten patients included were severe. There is a study published in Molecular Nutrition & Food Research in 2012 regarding pine nut allergy (clinical features and major allergens characterization). Are there any studies evaluating cross-reactivity between pine nuts and either tree nuts or seeds? Pine nuts are generally considered a seed. I'm often asked whether pine nuts should be avoided in other tree nut allergic patients. I am writing concerning the following question posted on : Beatriz Cabanillas, who sent us some very helpful additional information to our original response. We have heard from one of our readers and one of our AAAAI members, Dr. ![]() Anaphylaxis induced by pine nuts in two young girls. Ibanez MD, Lombardero M, San Ireneo MM, Munoz MC. Allergy to pine nuts in children.Īllerg Immunol (Paris) 1998 30(7):212-6.Ĥ. A MA, Maselli JP, Sanz Mf ML, Fernandez-Benitez M. Thank you again for your inquiry and we hope this response is helpful to you.ġ. However, in most instances, we advise that patients who are allergic to nuts to avoid all nuts, including pine "nuts". The issue, therefore, of whether pine nuts should be avoided in patients who are allergic to nuts and seeds can only be decided by clinical judgment. It is not known whether patients who have shown anaphylactic sensitivity to pine nuts as well as other nuts or seeds do so because of cross-reacting antigens or the fact that they simply are reacting separately because of their highly atopic nature. Thus, unfortunately, we cannot give you a definitive answer as to which nuts or other foods might be cross-reactive in your patient except to say that crossreactivity evidently does occur and has been demonstrated to almonds and peanuts. In addition, there are patients who have had anaphylactic episodes to pine nuts who have demonstrated allergy to other nuts as well (3), but there are also patients who were only mono-sensitized to the pine nut (4). There is one study which showed crossreactivity with peanuts (1), and another with almonds (2). However, there is very little information on potential crossreactivity between pine nuts and other foods, including nuts. We do not know, unfortunately, the major allergen of pine nuts, but there are several studies which have isolated components which were allergenic in the particular patients evaluated. ![]() You are correct that pine nuts are actually seeds.
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